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Her attitude really irritated me.

His incompetence began to irritate everyone.

Doesn't it irritate you to see couples making out around town?

Flashy people irritate him.

Tom purposely wore his shirt inside out just to irritate Mary.

It irritated my throat.

irritate your skin

I can't think of anything that irritates me.

The fact seemed to irritate her husband.

The substance can irritate or corrode the skin, eyes, or mucous membranes.